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Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 97-104 doi: 10.15302/J-FASE-2018248

Abstract:

Plant nucleotide binding domain and leucine-rich repeat (NLR) receptors recognize pathogen effectors

Keywords： E3 ubiquitin ligase     degradation     nucleotide-binding leucine-rich repeat receptor     plant immunity     proteasome    

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Pseudomonas Cyclic Lipopeptide Medpeptin: Biosynthesis and Modulation of Plant Immunity Article

Yi-Lin Gu, Jun-Zhou Li, Yan Li, Shen Cong, Jing Wang, Yi-Nan Ma, Hai-Lei Wei

Engineering 2023, Volume 28, Issue 9,   Pages 153-165 doi: 10.1016/j.eng.2023.05.016

Abstract: Silencing of a cell-wall leucine-rich repeat extensin protein (NbLRX3) or a receptor-like protein kinase

Keywords： Pseudomonas     Cyclic lipopeptide     Cell death     Leucine-rich repeat extension (LRX)     Medpeptin     Receptor-like    

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Carcinogens that induce the A:T>T:A nucleotide substitutions in the genome

Guangbiao Zhou, Xinchun Zhao

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 236-238 doi: 10.1007/s11684-017-0611-y

Abstract: Province of China, and 47% to 1.7% of HCCs from the Chinese mainland and other countries harbored the nucleotide

Keywords： genomic signature     carcinogen     aristolochic acid     tobacco smoke     vinyl chloride     hepatocellular carcinoma    

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Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 378-388 doi: 10.1007/s11684-021-0840-y

Abstract: The Fc fragment of the IgG-binding protein (FCGBP) was identified as the most promising indicator of

Keywords： severe Mycoplasma pneumoniae pneumonia     children     proteomics     Fc fragment of the IgG-binding protein    

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Chloride binding and time-dependent surface chloride content models for fly ash concrete

S. MUTHULINGAM,B. N. RAO

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 1,   Pages 112-120 doi: 10.1007/s11709-015-0322-x

Abstract: fly ash concrete, namely: 1) surface chloride content under tidal exposure condition; and 2) chloride bindingFirst, inconsistencies in surface chloride content and chloride binding models reported in literatureSecondly, to avoid such inconsistencies, surface chloride content and chloride binding models for fly

Keywords： binding isotherms     chloride ingress     concrete     fly ash     surface chloride content    

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Ether-/Ester-/Fluorine-Rich Binding Emulsion Formula for Lithium-Ion Batteries Article

Xianqing Zeng, Donglin Han, Zeheng Li, Hongxun Wang, Gu Wu, Yong Deng, Kai Liu, Li Xie, Chengdu Liang, Min Ling, Yuchuan Huang

Engineering 2022, Volume 19, Issue 12,   Pages 199-206 doi: 10.1016/j.eng.2022.05.020

Abstract: properties, stability, and compatibility with the electrolyte solution, and design an ether-/ester-/fluorine-rich

Keywords： Silicon anode     Emulsion copolymerization     Fluorine atom     Ether     Ester    

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Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases

Chong Liu, Dingfeng Su

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 35-40 doi: 10.1007/s11684-012-0171-0

Abstract: cholinergic anti-inflammatory pathway,” more specifically via the α7 nicotinic acetylcholine receptor

Keywords： α7 nicotinic acetylcholine receptor     cardiovascular diseases     baroreflex sensitivity    

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reduces IgE binding ability of allergenic egg white proteins

Sen LI, Marina OFFENGENDEN, Michael G. GÄNZLE, Jianping WU

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 373-381 doi: 10.15302/J-FASE-2018210

Abstract: objective of this study was to investigate the effect of Aspergillus oryzae cultivation on IgE bindingAdding mycelium of A. oryzae ATCC 1011 and 16868 substantially reduced the IgE binding abilityThe binding capacity of egg white proteins to IgE in plasma from four egg allergy patients was almostTherefore, the reduction of IgE binding ability of egg white proteins during A. oryzae treatment

Keywords： Aspergillus oryzae     egg allergy     egg white proteins     IgE-binding ability     ovomucoid    

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Nitrifying population dynamics in a redox stratified membrane biofilm reactor (RSMBR) for treating ammonium-rich

Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 1,   Pages 48-56 doi: 10.1007/s11783-011-0305-7

Abstract: redox stratified membrane biofilm reactor (RSMBR) under oxygen limited condition to treat ammonium-rich

Keywords： ammonium-rich wastewater     membrane biofilm reactor     nitrification     redox stratification     shortcut nitrogen    

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Quantitative characterization of Cu binding potential of dissolved organic matter (DOM) in sediment from

Yuan ZHANG,Yan ZHANG,Tao YU

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5,   Pages 666-674 doi: 10.1007/s11783-013-0608-y

Abstract: sediment samples were collected from various part of Taihu Lake to explore the spatial difference in the bindingThe ISE results showed that the exogenous DOM had higher binding ability than endogenous DOM, and DOMderived from aquatic macrophytes had a higher binding ability than that derived from algae.

Keywords： binding ability     dissolved organic matters     fluorescence quenching     complex capacity     Taihu Lake    

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Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 420-429 doi: 10.1007/s11684-016-0478-3

Abstract: Furthermore, all-trans retinoic acid treatment induced CDKN2C expression by releasing the PML/RARα binding

Keywords： CDKN2C     acute promyelocytic leukemia     cell cycle arrest     differentiation    

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Mechanism and control factors of hydrate plugging in multiphase liquid-rich pipeline flow systems: a

Shuwei ZHANG, Liyan SHANG, Zhen PAN, Li ZHOU, You GUO

Frontiers in Energy 2022, Volume 16, Issue 5,   Pages 747-773 doi: 10.1007/s11708-022-0830-z

Abstract: the significant research efforts specializing in the mechanisms of hydrate blockages in the liquid-rich

Keywords： hydrate     flow rate     water content     mechanism of pipeline blockage     rich liquid phase system    

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Platelet-rich plasma: combinational treatment modalities for musculoskeletal conditions

Isabel Andia, Michele Abate

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 139-152 doi: 10.1007/s11684-017-0551-6

Abstract: Platelet-rich plasma therapies have emerged as a potential approach to enhance tissue repair and regenerationPlatelet-rich plasma application aims to provide supraphysiological concentrations of platelets and optionallyHowever, the efficacy of platelet-rich plasma is controversial in chronic diseases because patients&rsquoIn this review, the interactions between platelet-rich plasma and healing mechanisms were addressed andThe development of combinational platelet-rich plasma treatments that can be used safely and effectively

Keywords： regenerative medicine     joint conditions     muscle injuries     platelet rich plasma     tendinopathy     healing mechanisms    

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Resistance to receptor tyrosine kinase inhibition in cancer: molecular mechanisms and therapeutic strategies

Peter B. Alexander,Xiao-Fan Wang

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 134-138 doi: 10.1007/s11684-015-0396-9

Abstract: In this review, we discuss the main known mechanisms of resistance to receptor tyrosine kinase inhibitorsoutput, and consider the problems of signaling pathway redundancy and how the activation of different receptor

Keywords： targeted therapy     drug resistance     receptor tyrosine kinases     cancer    

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Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factorreceptor 2-negative (HR

Wenjie Zhu, Binghe Xu

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 208-220 doi: 10.1007/s11684-020-0795-4

Abstract: New targeted therapies have been developed to overcome resistance to endocrine therapy (ET) and improve the outcome of HR /HER2 advanced breast cancer (ABC). We conducted a meta-analysis and systemic review on randomized controlled trials evaluating various targeted therapies in combination with ET in HR /HER2 ABC. PUBMED and EMBASE databases were searched for eligible trials. Hazard ratios (HRs) for progression-free survival (PFS), odds ratios (ORs) for objective response rate (ORR), clinical benefit rate (CBR), and toxicity were meta-analyzed. Twenty-six studies with data on 10 347 patients were included and pooled. The addition of cyclin-dependent kinase 4/6 inhibitors to ET significantly improved median PFS (pooled HR= 0.547, <0.001), overall survival (pooled HR= 0.755, <0.001), and tumor response rates (ORR, pooled OR= 1.478, <0.001; CBR, pooled OR= 1.201, <0.001) with manageable toxicities (pooled OR= 3.280, <0.001). The mammalian targets of rapamycin inhibitors and exemestane were not clinically beneficial for this pooled population including ET-naïve and ET-resistant patients. Moderate improvement in PFS (pooled HR= 0.686, <0.001) yet pronounced toxicities (pooled OR= 2.154, <0.001) were noted in the combination of phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitors with fulvestrant. Future studies are warranted to optimize the population and the dosing sequence of these available options.

Keywords： endocrine-resistant     HR+/HER2- advanced breast cancer     randomized clinical trials     meta-analysis     targeted therapy    

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Title Author Date Type Operation

Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Journal Article

Pseudomonas Cyclic Lipopeptide Medpeptin: Biosynthesis and Modulation of Plant Immunity

Yi-Lin Gu, Jun-Zhou Li, Yan Li, Shen Cong, Jing Wang, Yi-Nan Ma, Hai-Lei Wei

Journal Article

Carcinogens that induce the A:T>T:A nucleotide substitutions in the genome

Guangbiao Zhou, Xinchun Zhao

Journal Article

Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein

Journal Article

Chloride binding and time-dependent surface chloride content models for fly ash concrete

S. MUTHULINGAM,B. N. RAO

Journal Article

Ether-/Ester-/Fluorine-Rich Binding Emulsion Formula for Lithium-Ion Batteries

Xianqing Zeng, Donglin Han, Zeheng Li, Hongxun Wang, Gu Wu, Yong Deng, Kai Liu, Li Xie, Chengdu Liang, Min Ling, Yuchuan Huang

Journal Article

Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases

Chong Liu, Dingfeng Su

Journal Article

reduces IgE binding ability of allergenic egg white proteins

Sen LI, Marina OFFENGENDEN, Michael G. GÄNZLE, Jianping WU

Journal Article

Nitrifying population dynamics in a redox stratified membrane biofilm reactor (RSMBR) for treating ammonium-rich

Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO

Journal Article

Quantitative characterization of Cu binding potential of dissolved organic matter (DOM) in sediment from

Yuan ZHANG,Yan ZHANG,Tao YU

Journal Article

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Journal Article

Mechanism and control factors of hydrate plugging in multiphase liquid-rich pipeline flow systems: a

Shuwei ZHANG, Liyan SHANG, Zhen PAN, Li ZHOU, You GUO

Journal Article

Platelet-rich plasma: combinational treatment modalities for musculoskeletal conditions

Isabel Andia, Michele Abate

Journal Article

Resistance to receptor tyrosine kinase inhibition in cancer: molecular mechanisms and therapeutic strategies

Peter B. Alexander,Xiao-Fan Wang

Journal Article

Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factorreceptor 2-negative (HR

Wenjie Zhu, Binghe Xu

Journal Article